Calibration method in elasticity evaluation of regenerating cartilage based on ultrasonic particle velocity

Naotaka Nitta, Koji Hyodo, Masaki Misawa, Kazuhiko Hayashi, Yoshio Shirasaki, Kazuhiro Homma, Tsuyoshi Shiina

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

It is important in regenerative medicine to evaluate the maturity of regenerating tissue. In the maturity evaluation of regenerating cartilage, it is useful to measure the temporal change in elasticity because the maturity of regenerating tissue is closely related to its elasticity. In this study, a quantitative elasticity evaluation of extracted regenerating cartilage samples, which is based on the laser Doppler measurement of ultrasonic particle velocity and calibration, was experimentally investigated using agar-based phantoms with different Young's moduli and regenerating cartilage samples extracted from beagles in animal experiments. The experimental results verified the feasibility of the proposed method for the elasticity evaluation of regenerating cartilage samples.

Original languageEnglish
Article number07HF24
JournalJapanese Journal of Applied Physics
Volume52
Issue number7 PART 2
DOIs
Publication statusPublished - 2013 Jul
Externally publishedYes

ASJC Scopus subject areas

  • General Engineering
  • General Physics and Astronomy

Fingerprint

Dive into the research topics of 'Calibration method in elasticity evaluation of regenerating cartilage based on ultrasonic particle velocity'. Together they form a unique fingerprint.

Cite this