Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center

Midori Okada; Osamu Kitagawa; Tokushi Hanano; Takeo Taguchi

doi:10.1016/S0040-4020(97)00382-7

Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center

Midori Okada, Osamu Kitagawa, Tokushi Hanano, Takeo Taguchi

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

α-Iodination reaction of 4-alkenylamide with a β-chiral center proceeds with high diastereoseletivity to give syn α-iodoalkenamide through the formation of cyclic ketene N,O-acetal and subsequent α-iodination from the opposite side of a β-substituent.

Original language	English
Pages (from-to)	6825-6834
Number of pages	10
Journal	Tetrahedron
Volume	53
Issue number	20
DOIs	https://doi.org/10.1016/S0040-4020(97)00382-7
Publication status	Published - 1997 May 19
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4020(97)00382-7

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title = "Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center",

abstract = "α-Iodination reaction of 4-alkenylamide with a β-chiral center proceeds with high diastereoseletivity to give syn α-iodoalkenamide through the formation of cyclic ketene N,O-acetal and subsequent α-iodination from the opposite side of a β-substituent.",

author = "Midori Okada and Osamu Kitagawa and Tokushi Hanano and Takeo Taguchi",

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T1 - Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center

AU - Okada, Midori

AU - Kitagawa, Osamu

AU - Hanano, Tokushi

AU - Taguchi, Takeo

PY - 1997/5/19

Y1 - 1997/5/19

N2 - α-Iodination reaction of 4-alkenylamide with a β-chiral center proceeds with high diastereoseletivity to give syn α-iodoalkenamide through the formation of cyclic ketene N,O-acetal and subsequent α-iodination from the opposite side of a β-substituent.

AB - α-Iodination reaction of 4-alkenylamide with a β-chiral center proceeds with high diastereoseletivity to give syn α-iodoalkenamide through the formation of cyclic ketene N,O-acetal and subsequent α-iodination from the opposite side of a β-substituent.

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DO - 10.1016/S0040-4020(97)00382-7

M3 - Article

AN - SCOPUS:0030929362

SN - 0040-4020

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JO - Tetrahedron

JF - Tetrahedron

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ER -

Diastereoselective α-iodination reaction of 4-alkenylamide having a β-chiral center

Abstract

ASJC Scopus subject areas

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