The Diels-Alder reaction of N-allylic enamide and α,β-unsaturated lactam derivatives proceeded in the presence of I2 at low temperature through a cationic iodolactonization intermediate. With some substrates, this method of activation was proved to be more effective than by use of Lewis acids.
|Number of pages||4|
|Publication status||Published - 1995 Jan 23|
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry