Dispensing of mono-dispersed micro-bubbles for cell ablation

Hiroki Kuriki; Yoko Yamanishi; Shinya Sakuma; Satoshi Akagi; Fumihito Arai

doi:10.1109/ICRA.2013.6630961

Dispensing of mono-dispersed micro-bubbles for cell ablation

Hiroki Kuriki, Yoko Yamanishi, Shinya Sakuma, Satoshi Akagi, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have successfully produced mono-dispersed micro-gas bubbles for less than around 10 μm diameter by micro-bubble knife which produce micro-bubble in an electrically induced ultrasonic field. The discharged output power and conductive area of micro-electrode in micro-bubble knife which cuts the cell by micro-bubble were controlled by glass shell insulation around the copper micro-wire. A small space which is called 'bubble reservoir' between the wire and glass tip contributes to stabilize the electric discharge and directional bubble generation. The directionally dispensed bubbles can be used for processing of soft materials such as biological cells. For the present study the cell membrane has successfully processed with a few μm order resolution.

Original language	English
Title of host publication	2013 IEEE International Conference on Robotics and Automation, ICRA 2013
Pages	2783-2788
Number of pages	6
DOIs	https://doi.org/10.1109/ICRA.2013.6630961
Publication status	Published - 2013
Event	2013 IEEE International Conference on Robotics and Automation, ICRA 2013 - Karlsruhe, Germany Duration: 2013 May 6 → 2013 May 10

Publication series

Name	Proceedings - IEEE International Conference on Robotics and Automation
ISSN (Print)	1050-4729

Other

Other	2013 IEEE International Conference on Robotics and Automation, ICRA 2013
Country/Territory	Germany
City	Karlsruhe
Period	13/5/6 → 13/5/10

ASJC Scopus subject areas

Software
Control and Systems Engineering
Artificial Intelligence
Electrical and Electronic Engineering

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10.1109/ICRA.2013.6630961

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Dispensing of mono-dispersed micro-bubbles for cell ablation. / Kuriki, Hiroki; Yamanishi, Yoko; Sakuma, Shinya et al.

2013 IEEE International Conference on Robotics and Automation, ICRA 2013. 2013. p. 2783-2788 6630961 (Proceedings - IEEE International Conference on Robotics and Automation).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kuriki, H, Yamanishi, Y, Sakuma, S, Akagi, S & Arai, F 2013, Dispensing of mono-dispersed micro-bubbles for cell ablation. in 2013 IEEE International Conference on Robotics and Automation, ICRA 2013., 6630961, Proceedings - IEEE International Conference on Robotics and Automation, pp. 2783-2788, 2013 IEEE International Conference on Robotics and Automation, ICRA 2013, Karlsruhe, Germany, 13/5/6. https://doi.org/10.1109/ICRA.2013.6630961

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abstract = "We have successfully produced mono-dispersed micro-gas bubbles for less than around 10 μm diameter by micro-bubble knife which produce micro-bubble in an electrically induced ultrasonic field. The discharged output power and conductive area of micro-electrode in micro-bubble knife which cuts the cell by micro-bubble were controlled by glass shell insulation around the copper micro-wire. A small space which is called 'bubble reservoir' between the wire and glass tip contributes to stabilize the electric discharge and directional bubble generation. The directionally dispensed bubbles can be used for processing of soft materials such as biological cells. For the present study the cell membrane has successfully processed with a few μm order resolution.",

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AB - We have successfully produced mono-dispersed micro-gas bubbles for less than around 10 μm diameter by micro-bubble knife which produce micro-bubble in an electrically induced ultrasonic field. The discharged output power and conductive area of micro-electrode in micro-bubble knife which cuts the cell by micro-bubble were controlled by glass shell insulation around the copper micro-wire. A small space which is called 'bubble reservoir' between the wire and glass tip contributes to stabilize the electric discharge and directional bubble generation. The directionally dispensed bubbles can be used for processing of soft materials such as biological cells. For the present study the cell membrane has successfully processed with a few μm order resolution.

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Dispensing of mono-dispersed micro-bubbles for cell ablation

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