TY - GEN
T1 - Effect of sensory inputs on the motor evoked potentials in the wrist flexor muscle during the robotic passive stepping in humans
AU - Kitamura, Taku
AU - Nakajima, Tsuyoshi
AU - Yamamoto, Shin Ichiro
AU - Nakazawa, Kimitaka
PY - 2012/12/14
Y1 - 2012/12/14
N2 - The purpose of this study was to reveal whether the stepping-related afferent feedback modulates the motor evoked potentials (MEPs) in the wrist flexor muscle in humans. MEPs generated in flexor carpi radialis muscle (FCR) by transcranial magnetic stimulation (TMS) were recorded during robotic-assisted passive stepping and standing conditions. TMS were applied at fifteen scalp sites (3 × 5 cm grid in anterior-posterior direction and medial-lateral direction, respectively) centered on the hot spot which was defined as an optimal site for eliciting the MEP in FCR during passive standing task, The MEP amplitudes were measured for each stimulus sites, and then compared between different conditions. During passive stepping, the MEP amplitudes in FCR muscle were significantly increased in six adjacent stimulus sites of the hot spot, This result suggests that stepping-related afferent feedback induces expansion of excitatory area in motor cortex for FCR muscle.
AB - The purpose of this study was to reveal whether the stepping-related afferent feedback modulates the motor evoked potentials (MEPs) in the wrist flexor muscle in humans. MEPs generated in flexor carpi radialis muscle (FCR) by transcranial magnetic stimulation (TMS) were recorded during robotic-assisted passive stepping and standing conditions. TMS were applied at fifteen scalp sites (3 × 5 cm grid in anterior-posterior direction and medial-lateral direction, respectively) centered on the hot spot which was defined as an optimal site for eliciting the MEP in FCR during passive standing task, The MEP amplitudes were measured for each stimulus sites, and then compared between different conditions. During passive stepping, the MEP amplitudes in FCR muscle were significantly increased in six adjacent stimulus sites of the hot spot, This result suggests that stepping-related afferent feedback induces expansion of excitatory area in motor cortex for FCR muscle.
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U2 - 10.1109/EMBC.2012.6346810
DO - 10.1109/EMBC.2012.6346810
M3 - Conference contribution
C2 - 23366771
AN - SCOPUS:84870799930
SN - 9781424441198
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 3862
EP - 3865
BT - 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
T2 - 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
Y2 - 28 August 2012 through 1 September 2012
ER -