Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves

Mie Mitsui; Shoji Takeuchi; Takafumi Suzuki; Michiko Ohkura; Kunihiko Mabuchi

doi:10.1109/CNE.2003.1196757

Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves

Mie Mitsui, Shoji Takeuchi, Takafumi Suzuki, Michiko Ohkura, Kunihiko Mabuchi

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Citation (Scopus)

Abstract

We propose a flexible intra-fascicular nerve electrode for control of an artificial heart fabricated by micro machining techniques. We have studied methods for the control of an artificial heart by using autonomous nerve information. Though several approaches have been reported for chronic measurements from peripheral nerves, stable and long-term measurements from autonomous nerves have not yet been established. In order to realize stable and low-invasive measurements, we focused on the electrode's flexibility. Our electrode is fabricated on a flexible polyimide film using micro machining techniques. The electrode consists of four needle-shaped flexible probes. After the planar patterning process, the tips of each probe are bent perpendicularly for insertion into the nerve bundle. The recording sites are placed on the tips of the each probe for the purpose of contacting nondamaged nerve areas. Also the hook-shaped structures are fabricated near the tips to avoid tips and nerve bundle shifting. As a result of preliminary experiments, the thickness of the film that is able to be inserted into the vagal nerve bundle of goat is 75 μm. As a first step for the evaluation for the electrodes, we were able to successfully measure neural activities of the sciatic nerve bundle of rats.

Original language	English
Title of host publication	Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering
Editors	Laura J. Wolf, Jodi L. Strock
Publisher	IEEE Computer Society
Pages	67-70
Number of pages	4
ISBN (Electronic)	0780375793
DOIs	https://doi.org/10.1109/CNE.2003.1196757
Publication status	Published - 2003
Event	1st International IEEE EMBS Conference on Neural Engineering - Capri Island, Italy Duration: 2003 Mar 20 → 2003 Mar 22

Publication series

Name	International IEEE/EMBS Conference on Neural Engineering, NER
Volume	2003-January
ISSN (Print)	1948-3546
ISSN (Electronic)	1948-3554

Other

Other	1st International IEEE EMBS Conference on Neural Engineering
Country/Territory	Italy
City	Capri Island
Period	03/3/20 → 03/3/22

Keywords

Artificial heart
Control systems
Electrodes
Fabrication
Flexible printed circuits
Machining
Polyimides
Position measurement
Probes
Wires

ASJC Scopus subject areas

Artificial Intelligence
Mechanical Engineering

Access to Document

10.1109/CNE.2003.1196757

Cite this

Mitsui, M., Takeuchi, S., Suzuki, T., Ohkura, M., & Mabuchi, K. (2003). Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves. In L. J. Wolf, & J. L. Strock (Eds.), Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering (pp. 67-70). [1196757] (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2003-January). IEEE Computer Society. https://doi.org/10.1109/CNE.2003.1196757

Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves. / Mitsui, Mie; Takeuchi, Shoji; Suzuki, Takafumi et al.
Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering. ed. / Laura J. Wolf; Jodi L. Strock. IEEE Computer Society, 2003. p. 67-70 1196757 (International IEEE/EMBS Conference on Neural Engineering, NER; Vol. 2003-January).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Mitsui, M, Takeuchi, S, Suzuki, T, Ohkura, M & Mabuchi, K 2003, Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves. in LJ Wolf & JL Strock (eds), Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering., 1196757, International IEEE/EMBS Conference on Neural Engineering, NER, vol. 2003-January, IEEE Computer Society, pp. 67-70, 1st International IEEE EMBS Conference on Neural Engineering, Capri Island, Italy, 03/3/20. https://doi.org/10.1109/CNE.2003.1196757

Mitsui M, Takeuchi S, Suzuki T, Ohkura M, Mabuchi K. Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves. In Wolf LJ, Strock JL, editors, Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering. IEEE Computer Society. 2003. p. 67-70. 1196757. (International IEEE/EMBS Conference on Neural Engineering, NER). doi: 10.1109/CNE.2003.1196757

Mitsui, Mie ; Takeuchi, Shoji ; Suzuki, Takafumi et al. / Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves. Conference Proceedings - 1st International IEEE EMBS Conference on Neural Engineering. editor / Laura J. Wolf ; Jodi L. Strock. IEEE Computer Society, 2003. pp. 67-70 (International IEEE/EMBS Conference on Neural Engineering, NER).

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AB - We propose a flexible intra-fascicular nerve electrode for control of an artificial heart fabricated by micro machining techniques. We have studied methods for the control of an artificial heart by using autonomous nerve information. Though several approaches have been reported for chronic measurements from peripheral nerves, stable and long-term measurements from autonomous nerves have not yet been established. In order to realize stable and low-invasive measurements, we focused on the electrode's flexibility. Our electrode is fabricated on a flexible polyimide film using micro machining techniques. The electrode consists of four needle-shaped flexible probes. After the planar patterning process, the tips of each probe are bent perpendicularly for insertion into the nerve bundle. The recording sites are placed on the tips of the each probe for the purpose of contacting nondamaged nerve areas. Also the hook-shaped structures are fabricated near the tips to avoid tips and nerve bundle shifting. As a result of preliminary experiments, the thickness of the film that is able to be inserted into the vagal nerve bundle of goat is 75 μm. As a first step for the evaluation for the electrodes, we were able to successfully measure neural activities of the sciatic nerve bundle of rats.

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Flexible intra-fascicular nerve electrodes for the recordings of autonomous nerves

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