Geometrically-constrained cell manipulation for high speed and fine positioning

W. Fukui, M. Kaneko, T. Kawahara, Y. Yamanishi, F. Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

We succeeded in cell positioning with 1 [μm] resolution under the best tuning and with the maximum speed of 12 [cells/sec], by utilizing a PDMS chip including the micro channel whose diameter is slightly less than the cell to be handled. The key idea is that cell motion with originally six degrees of freedom (d.o.f) in free space is constrained to one d.o.f by pushing cell into a channel. Focusing on the positioning of cell in the micro channel, we also confirmed that the position control is stable due to enough viscous force between cell and wall of the channel.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages115-117
Number of pages3
Publication statusPublished - 2011
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2011 Oct 22011 Oct 6

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume1

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Country/TerritoryUnited States
CitySeattle, WA
Period11/10/211/10/6

Keywords

  • Geometrically-constrained cell manipulation
  • High speed vision
  • Micro channel
  • Position-adjustment-free

ASJC Scopus subject areas

  • Control and Systems Engineering

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