Abstract
Indirect anodic oxidation of β-phenylsulfenyl β-lactams was carried out using a catalytic amount of triarylamine as a mediator in acetonitrile containing fluoride ions; regioselective monofluorodesulfurization took place to give the corresponding β-fluorinated β-lactams in good yields. This is the first successful example of triarylamine-mediated anodic fluorodesulfurization.
| Original language | English |
|---|---|
| Pages (from-to) | 1269-1271 |
| Number of pages | 3 |
| Journal | Synlett |
| Issue number | 8 |
| Publication status | Published - 2001 Jan 1 |
| Externally published | Yes |
Keywords
- Electrochemical fluorination
- Fluoride salt
- Fluorodesulfurization
- Mediator
- β-lactam
ASJC Scopus subject areas
- Organic Chemistry