Laser manipulation of bio-/biomimetic materials

Toru Takasone, Saulius Juodkazis, Shigeki Matsuo, Akira Yamaguchi, Keiji Sasaki, Jun Ichi Hotta, Hiroaki Misawa

Research output: Contribution to journalConference articlepeer-review

2 Citations (Scopus)


We demonstrate a few examples of laser trapping and manipulation technique being applied for the measurements of small forces in the range of fN-pN and for laser microfabrication. We discuss prospective principles applicable for future nano/micro-mechanical tools. Elastic properties of microtubules of 24 nm in diameter were determined, a gold particle of 0.25 μm in diameter was laser trapped and manipulated. Paramagnetic microspheres were DNA-anchored to a glass substrate for measurement of elastic properties of DNA by evanescent light scattering. Also, a gold particle was attached to DNA and laser manipulated. The motion of the DNA molecule was controlled. The spring constant of the DNA was determined by using thermodynamical analysis of evanescent light scattering.

Original languageEnglish
Pages (from-to)212-217
Number of pages6
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 2002
Externally publishedYes
EventThird International Symposium on Laser Precision Microfabrication - Osaka, Japan
Duration: 2002 May 272002 May 31


  • Elastic properties of DNA molecules
  • Evanescent light field
  • Laser manipulation
  • Laser trapping
  • Light pressure
  • Microtubule
  • Ponderomotive action of light

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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