Local ablation of a single cell using micro/nano bubbles

Hiroki Kuriki, Yoko Yamanishi, Shinya Sakuma, Satoshi Akagi, Fumihito Arai

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


We have successfully produced mono-dispersed microgas bubbles less than around 10 μm in diameter in an electrically induced ultrasonic field. The discharged output power and conductive area of the micro-electrode are controlled by glass shell insulation around the copper micro-wire. A small space between the wire and glass tip, a "bubble reservoir," contributes to the stabilization of the electric discharge and directional bubble generation. The directionally dispensed bubbles can be used for processing soft materials such as biological cells. For the present study, the cell membrane has successfully been processed with resolution of a few μm order and without any thermal collateral damage.

Original languageEnglish
Pages (from-to)476-483
Number of pages8
JournalJournal of Robotics and Mechatronics
Issue number3
Publication statusPublished - 2013 Jun


  • Ablation
  • Enucleation
  • Micro-bubble

ASJC Scopus subject areas

  • General Computer Science
  • Electrical and Electronic Engineering


Dive into the research topics of 'Local ablation of a single cell using micro/nano bubbles'. Together they form a unique fingerprint.

Cite this