TY - GEN
T1 - On-chip magnetically driven micro-robot for enucleation of oocyte
AU - Inomata, Naoki
AU - Mizunuma, Takehito
AU - Yamanishi, Yoko
AU - Kudo, Shogo
AU - Arai, Fumihito
PY - 2009
Y1 - 2009
N2 - We developed a magnetically driven microtool(MMT) used in a microfluidic chip for enucleation of oocyte. To achieve technological innovation, weight of the tool is about 1/300,000 compared with that of the conventional mechanical micromanipulator and was installed in a chip. We succeeded in precise positioning of the tool (5 μm) with low disturbances. The tool is actuated noncontact by the magnetic force, therefore, the microfluidic chip part is fully disposable with low cost. Of special notes are following. (1) Novel vibrating type of MMT is proposed to reduce the dead band of the magnetic actuation. (2) Omni-directional actuation of the tool was achieved by controlling magnetic field focused on a chip. (3) Backlash of the tool was reduced by supporting it by the flexible hinge with isotropic spring constant. (4) A polymer-metal hybrid structure which has properties of both elasticity and rigidity was employed for the tool. (5) Based on the novel and original design, we integrated a Robot-on-a-Chip (Robochip) and demonstrated on-chip enucleation of oocyte.
AB - We developed a magnetically driven microtool(MMT) used in a microfluidic chip for enucleation of oocyte. To achieve technological innovation, weight of the tool is about 1/300,000 compared with that of the conventional mechanical micromanipulator and was installed in a chip. We succeeded in precise positioning of the tool (5 μm) with low disturbances. The tool is actuated noncontact by the magnetic force, therefore, the microfluidic chip part is fully disposable with low cost. Of special notes are following. (1) Novel vibrating type of MMT is proposed to reduce the dead band of the magnetic actuation. (2) Omni-directional actuation of the tool was achieved by controlling magnetic field focused on a chip. (3) Backlash of the tool was reduced by supporting it by the flexible hinge with isotropic spring constant. (4) A polymer-metal hybrid structure which has properties of both elasticity and rigidity was employed for the tool. (5) Based on the novel and original design, we integrated a Robot-on-a-Chip (Robochip) and demonstrated on-chip enucleation of oocyte.
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U2 - 10.1109/MHS.2009.5351824
DO - 10.1109/MHS.2009.5351824
M3 - Conference contribution
AN - SCOPUS:77950959014
SN - 9781424450954
T3 - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
SP - 493
EP - 498
BT - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
T2 - 20th Anniversary MHS 2009 and Micro-Nano Global COE - 2009 International Symposium on Micro-NanoMechatronics and Human Science
Y2 - 8 November 2009 through 11 November 2009
ER -