Sniff-cam (bio-fluorometric gas-imaging system) for breath acetaldehyde after drinking

K. Iitani, M. Naisierding, T. Sato, K. Toma, T. Arakawa, K. Mitsubayashi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We developed Sniff-cam (bio-fluorometric gas-imaging system) for visualization of breath acetaldehyde (ACE) which is produced by ethanol metabolism in liver after drinking. Sniff-cam employed an alcohol dehydrogenase (ADH) immobilized cotton mesh with reduced nicotinamide adenine dinucleotide (NADH) for imaging of gaseous ACE distribution. NADH is consumed by ADH-mediated reduction of ACE, and its concentration and that of ACE are correlated. Therefore, imaging of gaseous ACE distribution was achieved by exciting NADH with an ultraviolet light-emitting diode array (340 nm wavelength) and recording the emitted fluorescence from NADH (490 nm wavelength) by a high sensitive camera. Decrement of fluorescence at around the gas outlet was observed when ACE vapor was introduced. This result demonstrates that the Sniff-cam could be applied for imaging of breath ACE.

Original languageEnglish
Title of host publicationChemical Sensors 12
Subtitle of host publicationChemical and Biological Sensors and Analytical Systems
EditorsM. Carter, Y. Shimizu, W. Y. Lee, T. Yasukawa, R. Mukundan, A. L. Simonian, L. A. Nagahara, O. Niwa, B. A. Chin
PublisherElectrochemical Society Inc.
Pages53-57
Number of pages5
Edition16
ISBN (Electronic)9781607687337, 9781607687672, 9781607687689, 9781607687696, 9781607687702, 9781607687719, 9781607687726, 9781607687733, 9781607687740, 9781607687757, 9781607687771, 9781607687788, 9781607687795, 9781607687801, 9781607687818, 9781607687825, 9781607687832, 9781607687849, 9781607687856, 9781607687863, 9781607687887, 9781607687894, 9781607687900, 9781607687917, 9781607687924, 9781607687931, 9781607687948, 9781607687955, 9781607687962, 9781607687979, 9781607687986, 9781607687993, 9781607688006, 9781607688013, 9781607688020, 9781607688037
DOIs
Publication statusPublished - 2016
Externally publishedYes
EventSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting - Honolulu, United States
Duration: 2016 Oct 22016 Oct 7

Publication series

NameECS Transactions
Number16
Volume75
ISSN (Print)1938-6737
ISSN (Electronic)1938-5862

Conference

ConferenceSymposium on Chemical Sensors 12: Chemical and Biological Sensors and Analytical Systems - PRiME 2016/230th ECS Meeting
Country/TerritoryUnited States
CityHonolulu
Period16/10/216/10/7

ASJC Scopus subject areas

  • General Engineering

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