The conformational and binding properties of ethylbipyridinio-modified β-Cyclodextrin using induced circular dichroism

Yi Qun Du; Asao Nakamura; Fujio Toda

doi:10.1007/BF01061075

The conformational and binding properties of ethylbipyridinio-modified β-Cyclodextrin using induced circular dichroism

Yi Qun Du, Asao Nakamura, Fujio Toda

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared with β-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of 1 (the spatial position of the ethyl viologen (C₂V²⁺) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).

Original language	English
Pages (from-to)	443-451
Number of pages	9
Journal	Journal of Inclusion Phenomena and Molecular Recognition in Chemistry
Volume	10
Issue number	4
DOIs	https://doi.org/10.1007/BF01061075
Publication status	Published - 1991 Jun 1
Externally published	Yes

Keywords

Cyclodextrin
binding ability
complex
conformation
ethyl viologen
steroidal guest

ASJC Scopus subject areas

Food Science
Chemistry(all)
Condensed Matter Physics

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10.1007/BF01061075

Cite this

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title = "The conformational and binding properties of ethylbipyridinio-modified β-Cyclodextrin using induced circular dichroism",

abstract = "The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared with β-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of 1 (the spatial position of the ethyl viologen (C2V2+) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).",

keywords = "Cyclodextrin, binding ability, complex, conformation, ethyl viologen, steroidal guest",

author = "Du, {Yi Qun} and Asao Nakamura and Fujio Toda",

year = "1991",

month = jun,

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doi = "10.1007/BF01061075",

language = "English",

volume = "10",

pages = "443--451",

journal = "Journal of Inclusion Phenomena and Molecular Recognition in Chemistry",

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T1 - The conformational and binding properties of ethylbipyridinio-modified β-Cyclodextrin using induced circular dichroism

AU - Du, Yi Qun

AU - Nakamura, Asao

AU - Toda, Fujio

PY - 1991/6/1

Y1 - 1991/6/1

N2 - The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared with β-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of 1 (the spatial position of the ethyl viologen (C2V2+) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).

AB - The conformational and binding properties of mono-6-deoxy-6[4-(1-ethyl-4-pyridinio)-1-pyridinio]-β-cyclodextrin (1) in complex formation with some guest compounds were examined by induced circular dichroism (ICD) spectra in aqueous solution. Compound 1 showed much stronger binding ability for some guest compounds (1: 1 complexes), compared with β-cyclodextrin (β-CDx) and a positively charged β-CDx [C-6-mono-pyridino-β-CDx (2)]. Marked conformational changes of 1 (the spatial position of the ethyl viologen (C2V2+) group relative to the cavity in 1) were observed upon complex formation with some guests like 1-adamantanecarboxylic acid (ACA) and sodium cholate (SC).

KW - Cyclodextrin

KW - binding ability

KW - complex

KW - conformation

KW - ethyl viologen

KW - steroidal guest

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U2 - 10.1007/BF01061075

DO - 10.1007/BF01061075

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VL - 10

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JO - Journal of Inclusion Phenomena and Molecular Recognition in Chemistry

JF - Journal of Inclusion Phenomena and Molecular Recognition in Chemistry

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ER -

The conformational and binding properties of ethylbipyridinio-modified β-Cyclodextrin using induced circular dichroism

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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