Ablation catheter–induced mechanical deformation in myocardium: computer modeling and ex vivo experiments

Yukako Ijima, Kriengsak Masnok, Juan J. Perez, Ana González-Suárez, Enrique Berjano, Nobuo Watanabe

研究成果: Article査読

1 被引用数 (Scopus)

抄録

Cardiac catheter ablation requires an adequate contact between myocardium and catheter tip. Our aim was to quantify the relationship between the contact force (CF) and the resulting mechanical deformation induced by the catheter tip using an ex vivo model and computational modeling. The catheter tip was inserted perpendicularly into porcine heart samples. CF values ranged from 10 to 80 g. The computer model was built to simulate the same experimental conditions, and it considered a 3-parameter Mooney-Rivlin model based on hyper-elastic material. We found a strong correlation between the CF and insertion depth (ID) (R2 = 0.96, P < 0.001), from 0.7 ± 0.3 mm at 10 g to 6.9 ± 0.1 mm at 80 g. Since the surface deformation was asymmetrical, two transversal diameters (minor and major) were identified. Both diameters were strongly correlated with CF (R2 ≥ 0.95), from 4.0 ± 0.4 mm at 20 g to 10.3 ± 0.0 mm at 80 g (minor), and from 6.4 ± 0.7 mm at 20 g to 16.7 ± 0.1 mm at 80 g (major). An optimal fit between computer and experimental results was achieved, with a prediction error of 0.74 and 0.86 mm for insertion depth and mean surface diameter, respectively. Graphical Abstract: (Figure presented.).

本文言語English
ページ(範囲)3283-3292
ページ数10
ジャーナルMedical and Biological Engineering and Computing
62
11
DOI
出版ステータスPublished - 2024 11月

ASJC Scopus subject areas

  • 生体医工学
  • コンピュータ サイエンスの応用

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