Adaptive and quantitative reconstruction algorithm for photoacoustic tomography

Shuhui Bu, Kengo Kondo, Makoto Yamakawa, Tsuyoshi Shiina, Kazuhiko Fukutani, Yasuhiro Someda, Yasufumi Asao

研究成果: Conference contribution

3 被引用数 (Scopus)


Photoacoustic (PA) tomography is a rapidly developing imaging modality which can provide high contrast and spatial-resolution images of light absorption distribution in tissue. However, the quantitative reconstruction of absorption distribution is still a challenge. In this study, we propose an adaptive and quantitative reconstruction algorithm for reducing amplification of noises and artifacts in deep position due to light fluence compensation. In this method, the quantitative processing is integrated into the iterative reconstruction, and absorption coefficient distribution is iteratively updated. At each iteration step, the residual is calculated from detected PA signals and the signals calculated from a forward model by using the initial pressure which is calculated from the production of voxel value and the light fluence. By minimizing the residual, the reconstructed values are converged to the true absorption coefficient distributions. Since this method uses a global optimized compensation, better CNR can be obtained. The results of simulation and phantom experiment indicate that the proposed method provide better CNR at deep region. We expect that the capability of increasing imaging depth will broaden clinical applications.

ホスト出版物のタイトルPhotons Plus Ultrasound
ホスト出版物のサブタイトルImaging and Sensing 2011
出版ステータスPublished - 2011
イベントPhotons Plus Ultrasound: Imaging and Sensing 2011 - San Francisco, CA, United States
継続期間: 2011 1月 232011 1月 25


名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2011
国/地域United States
CitySan Francisco, CA

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 生体材料
  • 原子分子物理学および光学
  • 放射線学、核医学およびイメージング


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