Amino disaccharides having an alpha-(1-->4) or a beta-(1-->4) linkage, their synthesis and evaluation as a potential inhibitor for HIV-1 TAR-Tat.

Takashi Iguchi; Hirohumi Ishikawa; Hiroharu Matumoto; Mamoru Mizuno; Kohtaro Goto; Keita Hamasaki

doi:10.1093/nass/49.1.169

Amino disaccharides having an alpha-(1-->4) or a beta-(1-->4) linkage, their synthesis and evaluation as a potential inhibitor for HIV-1 TAR-Tat.

Takashi Iguchi, Hirohumi Ishikawa, Hiroharu Matumoto, Mamoru Mizuno, Kohtaro Goto, Keita Hamasaki

研究成果: Article › 査読

2 被引用数 (Scopus)

抄録

Amino disaccharides having an alpha-(1-->4) linkage or a beta-(1-->4) linkage have been prepared as the mimics of amino glycoside antibiotics and their inhibition for HIV-1 TAR-Tat were examined. The compound having alpha-(1-->4) linkage denotes better inhibition for TAR-Tat than that of the one having beta-(1-->4).

本文言語	English
ページ（範囲）	169-170
ページ数	2
ジャーナル	Nucleic acids symposium series (2004)
号	49
DOI	https://doi.org/10.1093/nass/49.1.169
出版ステータス	Published - 2005

ASJC Scopus subject areas

医学（全般）

文献へのアクセス

10.1093/nass/49.1.169

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引用スタイル

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AU - Goto, Kohtaro

AU - Hamasaki, Keita

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