Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA

Ichiro Kumagai; Tsuyoshi Takahashi; Keita Hamasaki; Akihiko Ueno; Hisakazu Mihara

doi:10.1016/S0960-894X(00)00006-8

Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA

Ichiro Kumagai, Tsuyoshi Takahashi, Keita Hamasaki, Akihiko Ueno, Hisakazu Mihara

研究成果: Article › 査読

1 被引用数 (Scopus)

抄録

Peptides containing peptide nucleic acid (PNA) have been designed and synthesized to construct molecules recognizing a bulge or a loop structure of RNA. Such peptides were here designed from the HIV Rev protein that can bind the stem-loop IIB of the Rev responsive element (RRE) RNA. Variations of PNA modulated the binding affinities of the peptides to RRE IIB RNA. (C) 2000 Elsevier Science Ltd. All rights reserved.

本文言語	English
ページ（範囲）	377-379
ページ数	3
ジャーナル	Bioorganic and Medicinal Chemistry Letters
巻	10
号	4
DOI	https://doi.org/10.1016/S0960-894X(00)00006-8
出版ステータス	Published - 2000 2月 21
外部発表	はい

ASJC Scopus subject areas

生化学
分子医療
分子生物学
薬科学
創薬
臨床生化学
有機化学

文献へのアクセス

10.1016/S0960-894X(00)00006-8

他のファイルとリンク

引用スタイル

@article{8b52bb8aa25f47ae8e8285bea16552cd,

title = "Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA",

abstract = "Peptides containing peptide nucleic acid (PNA) have been designed and synthesized to construct molecules recognizing a bulge or a loop structure of RNA. Such peptides were here designed from the HIV Rev protein that can bind the stem-loop IIB of the Rev responsive element (RRE) RNA. Variations of PNA modulated the binding affinities of the peptides to RRE IIB RNA. (C) 2000 Elsevier Science Ltd. All rights reserved.",

author = "Ichiro Kumagai and Tsuyoshi Takahashi and Keita Hamasaki and Akihiko Ueno and Hisakazu Mihara",

year = "2000",

month = feb,

day = "21",

doi = "10.1016/S0960-894X(00)00006-8",

language = "English",

volume = "10",

pages = "377--379",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Limited",

number = "4",

}

TY - JOUR

T1 - Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA

AU - Kumagai, Ichiro

AU - Takahashi, Tsuyoshi

AU - Hamasaki, Keita

AU - Ueno, Akihiko

AU - Mihara, Hisakazu

PY - 2000/2/21

Y1 - 2000/2/21

N2 - Peptides containing peptide nucleic acid (PNA) have been designed and synthesized to construct molecules recognizing a bulge or a loop structure of RNA. Such peptides were here designed from the HIV Rev protein that can bind the stem-loop IIB of the Rev responsive element (RRE) RNA. Variations of PNA modulated the binding affinities of the peptides to RRE IIB RNA. (C) 2000 Elsevier Science Ltd. All rights reserved.

AB - Peptides containing peptide nucleic acid (PNA) have been designed and synthesized to construct molecules recognizing a bulge or a loop structure of RNA. Such peptides were here designed from the HIV Rev protein that can bind the stem-loop IIB of the Rev responsive element (RRE) RNA. Variations of PNA modulated the binding affinities of the peptides to RRE IIB RNA. (C) 2000 Elsevier Science Ltd. All rights reserved.

UR - http://www.scopus.com/inward/record.url?scp=0034696079&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034696079&partnerID=8YFLogxK

U2 - 10.1016/S0960-894X(00)00006-8

DO - 10.1016/S0960-894X(00)00006-8

M3 - Article

C2 - 10714504

AN - SCOPUS:0034696079

SN - 0960-894X

VL - 10

SP - 377

EP - 379

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 4

ER -

Construction of HIV Rev peptides containing peptide nucleic acid that bind HIV RRE IIB RNA

抄録

ASJC Scopus subject areas

文献へのアクセス

他のファイルとリンク

フィンガープリント

引用スタイル