抄録
The reactions of various alkyl halides with the metallo enamines generated from racemic and optically pure N-C axially chiral mebroqualone derivatives were found to proceed with a synthetically attractive stereochemical outcome (up to 99% yield and up to dr = 26:1) allowing preparation of a structurally new type of pharmaceutically interesting compounds possessing elements of axial and central chirality.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 2650-2653 |
| ページ数 | 4 |
| ジャーナル | Organic Letters |
| 巻 | 19 |
| 号 | 10 |
| DOI | |
| 出版ステータス | Published - 2017 5月 19 |
ASJC Scopus subject areas
- 生化学
- 物理化学および理論化学
- 有機化学