TY - JOUR
T1 - Effect of spinal cord injury and its lesion level on stretch reflex modulation by cold stimulation in humans
AU - Ogata, H.
AU - Sayenko, D. G.
AU - Yamamoto, E.
AU - Kitamura, T.
AU - Yamamoto, S.
AU - Miyoshi, T.
AU - Kamibayashi, K.
AU - Nakazawa, K.
N1 - Funding Information:
This study was supported by a grant from the Japan Society for the Promotion of Science for Young Scientists.
PY - 2011/1
Y1 - 2011/1
N2 - Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21% of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11% in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20% in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.
AB - Objective: To determine how short-latency stretch reflex amplitude in the soleus muscle is modulated by cold stimulation in able-bodied individuals and individuals with complete spinal cord injury. Methods: An initial 100-s baseline period was followed by 50-s cold stimulation periods. Stretch reflex of the right soleus muscle was elicited for 10-s intervals, while cold stimulation was applied to the left thigh. Results: Peak-to-peak amplitude of the stretch reflex increased significantly during cold stimulation up to 127 ± 21% of the baseline in the able-bodied group (n= 9, P< 0.01). Similarly, stretch reflex increased up to 125 ± 11% in a group with injury level at or below thoracic 10 (n= 4), although this increase was not significant. On the other hand, stretch reflex decreased significantly down to 78 ± 20% in a group with injury level at or above thoracic 6 (n= 8, P< 0.05). Conclusions: Effect of afferent inputs induced by cold stimulation on stretch reflex modulation is different depending on the extent of central nervous systems participating in the modulation. Significance: Our findings provide a better understanding of some basic changes in afferent-efferent spinal reflex pathways which are probably not monosynaptic in nature.
KW - Autonomic dysreflexia
KW - Cardiovascular
KW - Somatic nervous system
KW - Spinal cord injuries
KW - Sympathetic nervous system
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U2 - 10.1016/j.clinph.2010.05.028
DO - 10.1016/j.clinph.2010.05.028
M3 - Article
C2 - 20580311
AN - SCOPUS:78650175146
SN - 1388-2457
VL - 122
SP - 163
EP - 170
JO - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
JF - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
IS - 1
ER -