TY - GEN
T1 - In vivo assessment method of tissue-engineered vascular wall based on quantitative elastic modulus measurement
AU - Nitta, Naotaka
AU - Yamane, Takashi
AU - Shin'oka, Toshiharu
AU - Matsumura, Goki
AU - Shiina, Tsuyoshi
PY - 2007
Y1 - 2007
N2 - Quantitative elastic modulus measurements of tissue-engineered (TE) vascular wall are useful for in vivo clinical follow-up because the elastic modulus is closely related with the biocompatibility, maturity and structural intensity of the vascular wall. While we have presented an in vitro measurement system for the TE vessel prior to grafting it in the previous study, we present a novel and specified method for in vivo assessment and follow-up of the TE vascular wall in this paper. Moreover, the regeneration score for in vivo assessment are also presented based on the measured quantitative elastic modulus. The effectiveness of the proposed assessment method was validated by in vivo experiment using canines.
AB - Quantitative elastic modulus measurements of tissue-engineered (TE) vascular wall are useful for in vivo clinical follow-up because the elastic modulus is closely related with the biocompatibility, maturity and structural intensity of the vascular wall. While we have presented an in vitro measurement system for the TE vessel prior to grafting it in the previous study, we present a novel and specified method for in vivo assessment and follow-up of the TE vascular wall in this paper. Moreover, the regeneration score for in vivo assessment are also presented based on the measured quantitative elastic modulus. The effectiveness of the proposed assessment method was validated by in vivo experiment using canines.
KW - Elastic modulus
KW - In vivo assessment; catheters
KW - Regeneration score
KW - Tissue-engineered vascular wall
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U2 - 10.1109/ULTSYM.2007.149
DO - 10.1109/ULTSYM.2007.149
M3 - Conference contribution
AN - SCOPUS:48149113765
SN - 1424413834
SN - 9781424413836
T3 - Proceedings - IEEE Ultrasonics Symposium
SP - 573
EP - 576
BT - 2007 IEEE Ultrasonics Symposium Proceedings, IUS
T2 - 2007 IEEE Ultrasonics Symposium, IUS
Y2 - 28 October 2007 through 31 October 2007
ER -