MARCKS regulates lamellipodia formation induced by IGF-I via association with PIP₂ and β-actin at membrane microdomains

Medicine & Life Sciences

• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 5%
• Actins 52%
• Cytosol 4%
• Detergents 4%
• Immunoprecipitation 4%
• Insulin-Like Growth Factor I 62%
• Lipids 21%
• Membrane Microdomains 86%
• Myristoylated Alanine-Rich C Kinase Substrate 100%
• Neomycin 5%
• Neurites 5%
• Phosphoinositide-3 Kinase Inhibitors 6%
• Phosphorylation 3%
• Protein C Inhibitor 5%
• Protein Kinase C 4%
• Protein Kinase Inhibitors 5%
• Pseudopodia 74%
• rho-Associated Kinases 5%
• Ro 31-8220 7%
• Y 27632 6%

Chemical Compounds

• Dephosphorylation 38%
• Insulin-Like Growth Factor I 95%
• Lipid 42%
• Lipid As 13%
• LY294002 18%
• Neomycin 14%
• Phosphatidylinositol 3 Kinase Inhibitor 17%
• Protein Kinase C Inhibitor 16%
• Rho Kinase Inhibitor 19%
• Ro 31-8220 21%