抄録
3-Trifluoromethylfuran (1) was efficiently synthesized by the reaction of 4-methyloxazole with 3, 3, 3-trifluoropropyne. Lithiation of 1 with n-butyllithium followed by reaction with an electrophile gave the corresponding 2-substituted 3-trifluoromethylfuran (4). Starting from 2-triethylsilyl-3-trifluoromethylfuran (4a), 2-substituted 4-trifluoromethylfurans (6) were synthesized.
本文言語 | English |
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ページ(範囲) | 3670-3674 |
ジャーナル | Chemical and Pharmaceutical Bulletin |
巻 | 33 |
号 | 9 |
出版ステータス | Published - 1985 |