Study for evaluation of skin aging with photoacoustic microscopy

Hiroki Hattori, Takeshi Namita, Kengo Kondo, Makoto Yamakawa, Tsuyoshi Shiina

研究成果: Conference contribution

2 被引用数 (Scopus)


Skin aging caused by ultraviolet light exposure is one of the serious problems from the viewpoint of beauty and healthcare. This is because ultraviolet light can cause age spot, wrinkles, at the worst case, skin cancer and so on. To evaluate skin aging, various modalities are being used, such as histopathological diagnosis, optical coherence tomography, ultrasound examination (B-mode imaging). However, they have disadvantages in terms of invasiveness, penetration depth and tissue specificity, respectively. To overcome these defects, photoacoustic imaging (PAI), a novel modality was used in this work. This modality can portray differences of tissue characteristics non-invasively. In this experiment, human skin tissues in various generations (i.e. various degrees of photo-aging) were measured by using optical resolution photoacoustic microscopy (OR-PAM) and acoustic resolution photoacoustic microscopy (AR-PAM). To verify the feasibility of quantitative skin aging evaluation with PA technique, signals from sectioned human skin (cheek and buttock; female from 28 to 95 years old) were measured with PA microscopy. The effects of photo-aging progress on the signal intensity were investigated. The results demonstrated that the PA signal from the dermis increases with aging progress. These analyses demonstrate the feasibility of quantitative skin aging evaluation with a PA imaging system.

ホスト出版物のタイトルPhotons Plus Ultrasound
ホスト出版物のサブタイトルImaging and Sensing 2020
編集者Alexander A. Oraevsky, Lihong V. Wang
出版ステータスPublished - 2020
イベントPhotons Plus Ultrasound: Imaging and Sensing 2020 - San Francisco, United States
継続期間: 2020 2月 22020 2月 5


名前Progress in Biomedical Optics and Imaging - Proceedings of SPIE


ConferencePhotons Plus Ultrasound: Imaging and Sensing 2020
国/地域United States
CitySan Francisco

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 原子分子物理学および光学
  • 生体材料
  • 放射線学、核医学およびイメージング


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