TY - JOUR
T1 - Synthesis, Characterization and Biomedical Application of Silver Nanoparticles
AU - Naganthran, Ashwini
AU - Verasoundarapandian, Gayathiri
AU - Khalid, Farah Eryssa
AU - Masarudin, Mas Jaffri
AU - Zulkharnain, Azham
AU - Nawawi, Norazah Mohammad
AU - Karim, Murni
AU - Abdullah, Che Azurahanim Che
AU - Ahmad, Siti Aqlima
N1 - Funding Information:
This project was financially supported by Universiti Putra Malaysia and Malaysia Ministry of Higher Education (MOHE) under the research grant attached to N.M. Nawawi, S.A. Ahmad, and M.M. Abd Karim (FRGS/1/2020/STG01/UNISEL/02/4). G.V. is funded by a personal scholarship (GRF) from Universiti Putra Malaysia. F.E.K. is funded by a personal scholarship from Majlis Amanah Rakyat (MARA).
Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2022/1/1
Y1 - 2022/1/1
N2 - Silver nanoparticles (AgNPs) have been employed in various fields of biotechnology due to their proven properties as an antibacterial, antiviral and antifungal agent. AgNPs are generally synthesized through chemical, physical and biological approaches involving a myriad of methods. As each approach confers unique advantages and challenges, a trends analysis of literature for the AgNPs synthesis using different types of synthesis were also reviewed through a bibliometric approach. A sum of 10,278 publications were analyzed on the annual numbers of publication relating to AgNPs and biological, chemical or physical synthesis from 2010 to 2020 using Microsoft Excel applied to the Scopus publication database. Furthermore, another bibliometric clustering and mapping software were used to study the occurrences of author keywords on the biomedical applications of biosynthesized AgNPs and a total collection of 224 documents were found, sourced from articles, reviews, book chapters, conference papers and reviews. AgNPs provides an excellent, dependable, and effective solution for seven major concerns: As antibacterial, antiviral, anticancer, bone healing, bone cement, dental applications and wound healing. In recent years, AgNPs have been employed in biomedical sector due to their antibacterial, antiviral and anticancer properties. This review discussed on the types of synthesis, how AgNPs are characterized and their applications in biomedical field.
AB - Silver nanoparticles (AgNPs) have been employed in various fields of biotechnology due to their proven properties as an antibacterial, antiviral and antifungal agent. AgNPs are generally synthesized through chemical, physical and biological approaches involving a myriad of methods. As each approach confers unique advantages and challenges, a trends analysis of literature for the AgNPs synthesis using different types of synthesis were also reviewed through a bibliometric approach. A sum of 10,278 publications were analyzed on the annual numbers of publication relating to AgNPs and biological, chemical or physical synthesis from 2010 to 2020 using Microsoft Excel applied to the Scopus publication database. Furthermore, another bibliometric clustering and mapping software were used to study the occurrences of author keywords on the biomedical applications of biosynthesized AgNPs and a total collection of 224 documents were found, sourced from articles, reviews, book chapters, conference papers and reviews. AgNPs provides an excellent, dependable, and effective solution for seven major concerns: As antibacterial, antiviral, anticancer, bone healing, bone cement, dental applications and wound healing. In recent years, AgNPs have been employed in biomedical sector due to their antibacterial, antiviral and anticancer properties. This review discussed on the types of synthesis, how AgNPs are characterized and their applications in biomedical field.
KW - Action mechanism
KW - AgNPs
KW - Biological
KW - Biomedical applications
KW - Biomedical properties of AgNPs
KW - Chemical
KW - Design and synthesis methods of silver nanoparticles
KW - Physical
UR - http://www.scopus.com/inward/record.url?scp=85123058657&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85123058657&partnerID=8YFLogxK
U2 - 10.3390/ma15020427
DO - 10.3390/ma15020427
M3 - Article
AN - SCOPUS:85123058657
SN - 1996-1944
VL - 15
JO - Materials
JF - Materials
IS - 2
M1 - 427
ER -