Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate

Rika Nakajima; Machiko Ono; Sadakazu Aiso; Hiroyuki Akita

doi:10.1248/cpb.53.684

Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate

Rika Nakajima, Machiko Ono, Sadakazu Aiso, Hiroyuki Akita

研究成果: Article › 査読

15 被引用数 (Scopus)

抄録

For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of the metabolites of MA, was synthesized from the commercially available methyl 4-hydroxyphenylacetate.

本文言語	English
ページ（範囲）	684-687
ページ数	4
ジャーナル	Chemical and Pharmaceutical Bulletin
巻	53
号	6
DOI	https://doi.org/10.1248/cpb.53.684
出版ステータス	Published - 2005 6月
外部発表	はい

ASJC Scopus subject areas

化学 (全般)
創薬

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title = "Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate",

abstract = "For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of the metabolites of MA, was synthesized from the commercially available methyl 4-hydroxyphenylacetate.",

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AU - Aiso, Sadakazu

AU - Akita, Hiroyuki

PY - 2005/6

Y1 - 2005/6

N2 - For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of the metabolites of MA, was synthesized from the commercially available methyl 4-hydroxyphenylacetate.

AB - For the purpose of the direct characterization of the intact conjugated form in the urine of a methamphetamine (MA) abuser, 4-hydroxymethamphetamine (4-OHMA) glucuronate, corresponding to one of the metabolites of MA, was synthesized from the commercially available methyl 4-hydroxyphenylacetate.

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KW - Glucuronate

KW - Synthesis

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Synthesis of methyl 1-O-(4-hydroxymethamphetaminyl)-α-D- glucopyranouronate

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